Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation.
نویسندگان
چکیده
The structures of new antifungal antibiotics, leptomycins A and B produced by Streptomyces sp. ATS1287 were determined as described below (Fig. 1) on the basis of their spectral and chemical character. Leptomycins have unique structures which belong to the unsaturated, branched-chain fatty acids with delta-lactone rings at the end.
منابع مشابه
Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization.
A strain of Streptomyces was found to produce new antifungal antibiotics. The active compounds were purified and separated into two substances named leptomycin A and B by high performance liquid chromatography. The molecular formulae of leptomycins A and B are C32H46O6 and C33H48O6 respectively, and physicochemical and biological properties of them are very similar to each other. Leptomycins A ...
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عنوان ژورنال:
- The Journal of antibiotics
دوره 36 6 شماره
صفحات -
تاریخ انتشار 1983